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Anesthesia Information and Emergency Medicine

Local Anesthetic Toxic Dose Calculator

Input the patient’s weight in pounds in the yellow box and press “enter” on your keyboard.
To calculate the toxic dose of a 1:1 mixture, mark the two corresponding yellow boxes with an “x”

-These calculations assume weight-based toxic doses as defined. Note, these can vary depending on manufacturer and country recommendations.

-These limits are based off recommendations for normal, healthy adults undergoing most routine procedures.

-Toxicity may depend on patient-specific, site-specific and block-specific factors and should be fully assessed on an individual basis.

-For more information on local anesthetic use and recommendations in podiatric surgery, refer to Kihm’s Podiatry Institute Update Article, 2011.

-Maximal total recommended doses: Lidocaine plain 300mg, Lidocaine with Epi 500mg; Marcaine plain 175mg, Marcaine with Epi 225mg.

-When weight-based limits exceed maximum total dose limits, maximum total doses are used.

-Lidocaine and marcaine are believed to have additive toxic effects in humans.

-Use at your own discretion. No liability is assumed for overadministration of local anesthetic.

Download the EXCEL Spreadsheet from here for further calculations.

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